Sharepoint and Auto-Create statistics

Sharepoint has built-in statistics that are optimized for how Sharepoint works.

For SharePoint 2010 it is not recommended to Auto-Create statistics for any databases.  Auto-Update statistics can be enabled for content databases if you are not manually updating statistics and you are experiencing performance issues.

For SharePoint 2013, enabling Auto-Create Statistics and Auto-Update Statistics is NOT supported.

https://docs.microsoft.com/en-us/SharePoint/administration/best-practices-for-sql-server-in-a-sharepoint-server-farm